Global Health Chronicles

Dr. Harold Jaffe

David J. Sencer CDC Museum, Global Health Chronicles
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1:07 - Introduction/Education

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Partial Transcript: So let’s begin a little bit with your background

Segment Synopsis: Dr. Jaffe talks about his childhood and the influences that led him to study medicine at UCLA.

Keywords: UC Berkeley; UCLA

Subjects: Jet Propulsion Lab; medical school; Medicine; Science

2:30 - Arrival at CDC

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Partial Transcript: How did you get interested in public health?

Segment Synopsis: Dr. Jaffe talks about his decision to go to CDC and his placement process.

Keywords: Epidemic Intelligence Service (EIS); Venereal Disease Control Division

Subjects: Centers for Disease Control and Prevention (CDC); U.S. Public Health Service

5:36 - First reported cases/surveillance

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Partial Transcript: Let’s shift our focus to your work on what was to become known as AIDS.

Segment Synopsis: Jaffe talks about the first reported AIDS cases and his role in surveillance and case definition during 1981.

Keywords: Bathhouse; case control study; case definition; D. Juranek; drugs; E. Braff; gay men; J. Curran; Los Angeles; M. Conant; MMWR; New York; P. Volberding; pportunistic infections; R. Bolan; S. Dritz; San Francisco; San Francisco Health Department; surveillance system; Task Force; UC San Francisco

Subjects: AIDS; Centers for Disease Control (CDC); Kaposi’s sarcoma (KS); pneumocystis (carinii pneumonia)

16:13 - First case control study

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Partial Transcript: As you got going; what was the atmosphere like among those working on the Task Force and what was the thinking as to what’s going on here that caused this?

Segment Synopsis: Dr. Jaffe talks about the first case control study and its associated challenges. He also talks about the study questionnaire and questions related to sexual practices of men.

Keywords: Atlanta; B. Darrow; bathhouse; Case control study; homosexual men; Los Angeles; M. Guinan; New York City; poppers; San Francisco; sexually transmitted disease (STD); W. Cates

Subjects: CDC; human immunodeficiency virus (HIV)

26:03 - Laboratory aspect of first case control study

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Partial Transcript: When you were interviewing those patients in the hotel rooms; were you getting laboratory specimens?

Segment Synopsis: Dr. Jaffe talks about the laboratory aspect of the first case control study and what they were looking for immunologically in the blood samples being collected.

Keywords: Atlanta; B. Evatt; blood; Division of Viral Diseases; J. Curran; J. Stewart; K. Hermann; M. Guinan; M. Rogers; New York; S. McDougal; T helper cell; T suppressor cell; T. Spira

Subjects: CDC

33:43 - Hemophilia/blood transfusion

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Partial Transcript: Moving away from the case control study to the investigation of cases of AIDS in hemophiliacs and transfusion recipients; so in July of ’82 there was an MMWR report on pneumocystis

Segment Synopsis: Dr. Jaffe talks about early hemophilia and transfusion cases including the death of a baby who had received multiple blood transfusions.

Keywords: A. Ammann; B. Evatt; blood supply; D. Lawrence; Division of Host Factors; hemophilia; Irwin Memorial Blood Bank; MMWR; opportunistic infections; transfusions; UC San Francisco

Subjects: AIDS (Acquired Immune Deficiency Syndrome); Pneumocystis

38:58 - CDC/public response to hemophilia cases

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Partial Transcript: That would had to be pretty alarming. What was the response among the task force and your-

Segment Synopsis: Dr. Jaffe talks about CDC; media; and public response to the hemophilia cases. Dr. Jaffe also talks about CDC media strategies for AIDS at this time.

Keywords: blood; children; media; MMWR; President Reagan

Subjects: AIDS; CDC; HIV

53:17 - CDC awareness of IV Drug use/Haitian AIDS cases

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Partial Transcript: We haven’t talked much about the IV drug users

Segment Synopsis: Dr. Jaffe talks about IV drug users and Hattian cases. He also discusses the Pasteur Institute’s discovery of a new retrovirus

Keywords: D. Francis; Dr. R. Gallo; drug use; Françoise Barré-Sinoussi; Haiti; Intravenous; IV; J.C. Chermann; L. Montagnier; Miami; New York; P. Feorino; Pasteur Institute; retrovirus; virology

Subjects: CDC; NIH

57:59 - CDC relationships with other federal agencies

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Partial Transcript: You mentioned the Kaposi’s Sarcoma meeting with NIH

Segment Synopsis: Dr. Jaffe talks about CDC’s relationship with other federal agencies like NIH and FDA during this time.

Keywords: G. Noble; J. Curran; R. Gallo; The U.S. Department of Health and Human Services; Washington (DC)

Subjects: CDC; FDA; HHS; NIH

60:11 - Political climate/media response

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Partial Transcript: Can you talk a little bit more about the political climate and even the climate among those infected; the gay community; drug users; Haitians during those early years.

Segment Synopsis: Dr. Jaffe talks about the effects of the Reagan administration on how the mainstream press effected CDC’s response to the emerging disease.

Keywords: activists; C. Everett Koop; gay press; President R. Reagan; R. Shilts; straight press

Subjects: AIDS; CDC

64:32 - Personal impact of Dr. Jaffe’s work on AIDS

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Partial Transcript: In closing; I’d like to ask you a few things about personal impact of your work on AIDS.

Segment Synopsis: Dr. Jaffe talks about the effects his work with AIDS had on his personal life and career

Keywords: blood; London; STD Division; virologist

Subjects: AIDS; CDC

66:44 - 1983 prevention recommendations

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Partial Transcript: So in early 1983; CDC issued prevention recommendations

Segment Synopsis: Dr. Jaffe talks about early CDC prevention recommendations and how they have changed since 1983.

Keywords: blood; blood bank; gay men; Haiti; intravenous drug users

Subjects: CDC; U.S. Public Health Service