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              <text>May 5, 1983, Curran, Chief, Epidemiology, AIDS Activity, May 23, Darrow, Braff, Dritz, Hawkins, O'Malley, Rendon, cooperative agreement, AIDS, homosexual, male, patients, San Francisco City Clinic, 1978, 1980, hepatis B, CDC, cohort, interview, data, laboratory specimen, residence, health, risk factors, control group, pilot program, national list, VD clinic record, Health Department, VD Control Division, Moss, sampling, death, interview form, data, medical evaluation, screening, San Francisco General Hospital, local, blood tests, mutually-agreed-upon-tests, Jaffe, </text>
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FROM: H. Jaffe, Chief, Epidemiology Section, AIDS Activity. &#13;
&#13;
TO: J. Curran, Director, AIDS Activity. &#13;
&#13;
RE: Implementation of Cooperative Agreement with the San Francisco City/County Health Department.&#13;
&#13;
 The focus to study homosexual male patients between 1978 and 1980, and enrolled in studies of the prevalence and incidence of hepatis B virus infection. Handwritten in the upper right corner "Darrow." </text>
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                <text>Protocol 639 Title: Acquired Immune Deficiency Syndrome in a Cohort of Homosexual Male Clinic Patients. &#13;
&#13;
Attachments: Access to Medical Records used in the City Clinic, Consent Forms, Patient Information Sheet (Handwritten note in red pen regarding confidentiality), Participation letter from the Department of Public Health City and County of San Francisco, Clinical Finding and 10 page questionnaire. </text>
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                <text>MEMORANDUM &#13;
&#13;
FROM: D. Koniver, Human Subjects Review Coordinator, Office of the Director, CDC &#13;
&#13;
TO: W. Darrow, AIDS Activity, CID. &#13;
&#13;
RE: Protocol #639, "Acquired Immune Deficiency Syndrome in a Cohort of Homosexual Male Clinic Patients" &#13;
&#13;
APPROVAL. Letter approving revised protocol. </text>
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&#13;
Background and introduction of the Prevalence Study, trends and conclusions, 5 pages of data.   </text>
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                <text>MEMORANDUM &#13;
&#13;
FROM: W. Darrow, Research Sociologists &#13;
&#13;
TO: J. Curran, Director, AIDS Program through H. Jaffe, Chief, Epidemiologist Studies Branch. &#13;
&#13;
RE: Acquired Immune Deficiency Syndrome in a Cohort of Homosexual Male Clinic Patients (Project 24): &#13;
&#13;
Update and Plans for further analyze study with an attached schematic outlining association of AIDS with social behavior and environmental risk factor measure in the various sources of data available. </text>
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                <text>Mathematical Model of the Spread of HTLV-III created by Robert H. Byers, W. Meade Morgan, William B. Darrow, Harold W. Jaffe, AIDS Branch and the Statistical sections. &#13;
&#13;
Homosexual men from San Francisco have been enrolled in a study for the prevalence and incidence of hepatitis B, blood samples have been kept and it is now possible to test or antibodies to the virus suspected to cause AIDS. &#13;
This report has a statistical model that will help answer some questions regarding the rate of spread of this virus. Handwritten upper right corner DARROW 3/15/85.   </text>
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